Chinedu S Aruah, Oyesegun R, Oche Ogbe, Igbinoba F, Okwor Vitalis, Abalu E, Madukwe J and Onyedika Okoye
National Hospital Abuja, Nigeria
University of Nigeria Teaching Hospital, Nigeria
Posters & Accepted Abstracts: J Cancer Sci Ther
Introduction: Many cancer patients present with anemia prior to radiotherapy and chemotherapy or may experience anemia/ worsening of anemia at some point during treatment. Aims & Objectives: The aim was to study impact of anemia in cancer patients undergoing radiotherapy and chemotherapy. Methodology: 201 cancer patients of both sexes with histopathologically confirmed malignancies (solid cancers) were included. Patient�s pre-treatment Hb was taken. Patients were distributed into radiotherapy, chemotherapy and chemoradiation. Their Hb was measured once every 2 weeks. The blood film pictures of the patients were examined. The whole process was terminated after 3 consecutive Hb reading or after week 6. Anemia was classified into: Less than 10 g/dl-severe anemia; 10-10.9 g/dl- moderate anemia; 11-12 g/dl-mild anemia; and 12 g/dl and above-no anemia. Results & Analysis: Out of 201 cancer patients, 86.1% were female and 13.9% were male. Age range was 25-75 years, 100 patients were on chemotherapy, 63 patients on radiotherapy and 38 patients on chemoradiation. The prevalence in anemia in cancer patients undergoing radiotherapy and chemotherapy was found to be 63% as shown by blood film picture (i.e. average of 72%, 42.9% and 73.7%). At the end of therapy, 62% (100) patients on chemotherapy and 55.6% (63) patients on radiotherapy had their Hb level between 11-12 g/dl, and 39.5% (38) cancer patients on chemoradiation arm had Hb value of 10-10.9 g/dl. At P- value>0.05, there was no statistical significance on distribution of mean Hb, standard deviation was based on sex and treatment type. Conclusion: Prevalence of anemia in the study group was found to be 63% while 37% had adequate hemoglobin (Hb) after the therapy as reflected in the blood film picture. At 95% confidence interval, chemotherapy had greatest impact on Hb level during therapy. Thus, chemotherapy: 9.60-10.62 g/dl; radiotherapy: 11.52-12.13 g/dl; and chemoradiation therapy: 10.98-11.36 g/dl was observed.
Email: aruasimeonedu@yahoo.com
Cancer Science & Therapy received 3968 citations as per Google Scholar report
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