Application of proteomic variations in personalized medicine of cancer

5^th Asia-Pacific Summit on Cancer Therapy

July 20-22, 2015 Brisbane, Australia

Xianquan Zihan

Posters Accepted Abstracts: J Cancer Sci Ther

Abstract :

Tumor heterogeneity and individual difference are actually derived from individualized variations. No two completely same individuals exist in the world. Variations are involved in each aspect of healthcare. Cancer contains highly heterogeneous cell types that are the distinguishing pathophysiological basis and causes the proteomic variation. In combination with multiple endogenous and exogenous factors, that proteome variation is the basis for personalized patient treatment. Differences in the proteins (the proteome) can distinguish among those heterogeneity structures. The components of a proteome dynamically change as a cancer progresses. Changes in protein expression, protein modifications, and protein molecular network, individually or in combination, might be biomarkers to predict the disease, monitor the tumor progression, and develop an accurate molecular classification for personalized patient treatment. The modalities of proteomic variation might also be useful in the interventional prevention and personalized treatment of patients to halt the occurrence and progression of a tumor.