Assessment of phytochemicals and antioxidant activities of raw and germinating Ceiba pentandra (kapok) seeds

2^nd International Conference and Exhibition on Pharmaceutical Regulatory Affairs

November 23-24, 2012 Hyderabad International Convention Centre, India

Ch. Ravi kiran

Accepted Abstracts: Pharmaceut Reg Affairs

Abstract :

The objective of this study was to determine the consequence of germination on phytochemical constituents and nonenzymatic activities of Ceiba pentandra seed extracts. The levels of phytochemical constituents tested are influenced by germination and showed increase except two constituents they are alkaloids and tannins, which are decreased significantly during germination. Among Non-enzymatic antioxidants like DPPH, FRAP, reducing assay and hydroxyl radicle scavenging activity all showed improved activity compared with non-germinating seeds, this may be due to, during germination, various reactive oxygen species (ROS) are generated as by products of metabolism. This group of ROS includes superoxide radicals (O2 -), hydrogen peroxide radicals (H2O2 -), and hydroxyl radicals (OH-). The formation of these oxygen radicals results in the accumulation of lipid hydroperoxides by radical chain oxidation via phospholipids peroxy radicals within membranes. Therefore, it was hypothesized that this could be related to the increase of antioxidant activity in large unilamellar vesicles observed in germinated seeds. The implication of this query is that the Ceiba pentandra seeds as natural antioxidant agents and put forward the possibility of employing for therapeutic potential.

Biography :

Ch.Ravi Kiran completed M.Phil in Department of Biochemistry, Andhra University and now he is pursuing his Ph.D in the same department. He Published more than 10 research articles in reputed journals.