Jozef Oleksyszyn
ScientificTracks: J Cancer Sci Ther
In the animal models of glucose dependent cancer growth, the growth is decreased 15-30% through the use of low- carbohydrate, calorically restricted and/or ketogenic diet. The remaining growth depends on glucose formed by the liver- kidney gluconeogenesis as is the case in the cancer cachexia. It is hypothesized that a new treatment for cancer diseases should be explored which includes the ketogenic diet combined with the inhibition of gluconeogenesis by the anti-diabetic drug metformin. Such treatment should induce the hypoglycemia with hypoxia similar to that observed during spontaneous remission of cancer.
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