Carboxylate-directed C-H allylation with allyl alcohols or ethers

9^th World Congress on Green Chemistry and Technology

September 17-19, 2018 | Amsterdam, Netherlands

Zhiyong Hu and Lukas J GooBen

Ruhr-Universitat Bochum, Germany

Posters & Accepted Abstracts: J Environ Anal Chem

Abstract :

A [Ru(p-cymene)Cl2]2 catalyst activates allyl alcohols and ethers for the regioselective ortho-Câ??H allylation of aromatic and heteroaromatic carboxylates. The reaction is orthogonal to most Câ??H functionalizations with allyl alcohols in that allyl arenes rather than carbonyl compounds are obtained. A wide range of substrates are thus smoothly transformed to allylarenes at 50°C in phosphate-buffered 2,2,2-trichloroethanol. The reaction concept combines the use of abundant reagents and directing groups in a sustainable, waste-minimized method for Câ??C bond formation.

Biography :

Zhiyong Hu has completed his Master’s degree from East China University of Science and Technology in China. Currently, he is pursuing his PhD at Ruhr- Universität Bochum, supervised by Lukas J Gooßen.

E-mail: Zhiyong.Hu@rub.de