Carica papaya leaf: Potent source of antimicrobial nanoparticles

2^nd International Conference on Food Chemistry & Nutrition

July 24-26, 2017 Vancouver, Canada

Ratika Komal and Vedpriya Arya

Guru Nanak Girls College, Punjab, India

Posters & Accepted Abstracts: J Exp Food Chem

Abstract :

The field of nanotechnology is one of the most active areas of research in modern materials science. Nanoparticles exhibited completely new or improved properties based on specific characteristics such as size, distribution and morphology. The use of environmentally benign materials like plant leaf extract, bacteria, fungi and enzymes for the synthesis of silver nanoparticles offers numerous benefits of eco-friendliness and compatibility for pharmaceutical and other biomedical applications as they do not use toxic chemicals for the synthesis protocol. The synthesis of metal nanoparticles using biological systems is an expanding research area due to the potential applications in nanomedicines. In the present study, Carica papaya leaf extract were treated with the 25 to 100 �¼m solution of silver nitrate. They resulted into the formation of silver nanoparticles of about 60 nm diameter. The silver nanoparticles were then centrifuged and a thin film is prepared for TEM evaluation which showed presence of silver nanoparticles. The UV-Vis spectrophotometer analysis also showed the presence of silver nanoparticles by showing absorption peak on 450 nm that is due to the SPR (Surface Plasmon Resonance) of silver nanoparticles. Using Agar disc method, 20-25 ml of crude extract of Carica papaya leaf using hot percolation method was used against clinically isolated pathogens. On other hand, 2.5-4.5 �¼l of silver nanoparticles obtained from crude extract Carica papaya leaf on subjection to different reaction conditions show clear 14 mm zone of inhibition against clinically isolated pathogens.

Biography :

Email: Ratika.komal@gmail.com