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C-H functionalisation of indazoles and azaindazoles
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Chemical Sciences Journal

ISSN: 2150-3494

Open Access

C-H functionalisation of indazoles and azaindazoles


19th Global Chemistry, Chromatography & Spectrometry Conference

March 20-21, 2019 | New York, USA

Said El Kazzouli

Euromed University of Fes,Morocco

Scientific Tracks Abstracts: Chem Sci J

Abstract :

Indazoles and azaindazoles, which are 6,5-fused heterocyclic systems containing two or three nitrogen atoms, are very important heteroaromatic compounds with applications in biology and materials sciences. Although the advances made in the synthesis and functionalization of indazoles and azaindazoles, Cā??H functionalization, which is a step and atom-economical transformation, remains the most attractive and advantageous procedure for the late-stage functionalization of indazoles and azaindazoles. They are five Cā??H bonds in indazoles and four C-H bonds in azaindazoles that can be functionalized, but these bonds are inequivalent. Thus, the development of new reactions that allow the regioselective functionalization of indazoles and azaindazoles is needed. This presentation will describe the recent advances made by our group1-7 and others in the Cā??H functionalization of indazoles and azaindazoles by direct arylation and oxidative alkenylation.

Biography :

E-mail: s.elkazzouli@ueuromed.org

 

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