Charcot neuroarthropathy following simultaneous pancreas-kidney transplant: A case report

Sports Nutrition and Ortho Congress

December 08-09, 2016 | Philadelphia, USA

Michael Wilson

WG (Bill) Hefner VA Medical Center, USA

Posters & Accepted Abstracts: J Sports Med Doping Stud

Abstract :

Charcot neuropathic arthropathy of the foot (CF) is a fairly common and devastating complication normally found in patients with long standing, mostly uncontrolled, diabetes. Occurring in up to 10 percent of the diabetic population, CF is characterized by a relatively painless, progressive and degenerative bone and joint destructive process with neuropathy and trauma as essential components. The absence of normal proprioceptive and protective mechanisms results in pathological fractures, deformity, and ulceration, with potential for limb loss. In the diabetic patient, concomitant risk factors for the development of CF include vascular disease, neuropathy, limited joint mobility, previous foot ulcer or amputation and nephropathy. Simultaneous pancreas-kidney transplantation (SPKT) is an accepted approach and treatment of choice in patients with type I diabetes with accompanying end stage renal disease (ESRD). Documented cases in the literature reveal CF as a post-transplant consequence. Traditional post-operative immunosuppressive therapy is identified as an additional risk factor for the development of de novo CF after SPKT. This report describes an unusual case of a patient who presented with a case of full-blown CF deformity with ulceration soon after SPKT. Post-SPKT immunosuppression therapy, particularly the use of corticosteroids, is acknowledged as a causative influence for the development of neuroarthropathy leading to CF.

Biography :

Email: michael.wilson9@va.gov