COPD due to sulfur mustard exposure

2^nd International Conference on Respiratory and Pulmonary Medicine

October 17-18, 2016 Chicago, USA

Hossein Rahmani, Iraj Javadi and Saeed Shirali

Islamic Azad University, Iran
Ahvaz Jundishapur University of Medical Sciences, Iran

Scientific Tracks Abstracts: J Pulm Respir Med

Abstract :

Sulfur mustard (SM) or bis(2-chloroethyl) sulfide is a vesicant and alkylating chemical weapon. SM was used in the 1980s against Iran by Iraqi forces. After exposure to SM in initial acute phase the greatest damage is incurred by the eyes, skin and the highest damage is caused to the lungs. This injury not only in the acute phase but also in the long-term has the highest prevalence among these patients. Clinical symptoms of people after exposure to SM start with irritation of the nose and sinuses in the mild doses to the runny nose and pain at higher doses and even irritation of the airways and bronchial engagement in very high doses. Respiratory complications in patients exposed to SM have been associated with long-term symptoms and these symptoms add to the intensity of the complication. Bloody sputum, feeling of tightness in the chest and shortness of breath over nights are among common symptoms; also the main respiratory symptoms including generalized wheezing, rale (crackle), decreased breath sounds and cyanosis and apparently, FEV1 is reduced by 50 mL/year. In these patients there are changes in blood cells especially, in white blood cells and neutrophils and systemic inflammation and systemic changes with other comorbidities are observed. Although SM pulmonary patientsâ�� treatment is based on bronchodilators and long-acting â���²2 agonists, paying attention to the comorbidities with prior systemic changes in these patients is a reason for the need to change treatment strategies of these patients with systemic and extra-pulmonary therapy.

Biography :

Hossein rahmani is working as a professor in Islamic Azad University, Iran. His international experience includes various programs, contributions and participation in different countries for diverse fields of study. His research interests reflect in his wide range of publications in various national and international journals.

Email: r.h1989@yahoo.com