COVID-19 as a trigger of recurrent Guillain-Barre Syndrome

Proceedings of Neurology 2021&Cognitive Neuroscience 2021&Child Psychology 2021

February 22-23, 2021 | Webinar

Nicole J. Altomare, Erin P. McDonnell, Yesha H. Parekh, Ram C. Gowda, Payal D. Parikh, Mark H. Lazar and Martin J. Blaser

Rutgers Robert Wood Johnson Medical School, USA

Posters & Accepted Abstracts: J Neurol Disord

Abstract :

Coronavirus 2019 (COVID-19) has been reported to trigger Guillain–BarreÃ�? syndrome (GBS). While uncommon, recurrent GBS (rGBS) episodes, triggered by antecedent viral infections, have been reported in a small proportion of GBS patients, here we describe a patient with a recurrent case of GBS, occurring secondary to COVID-19 infection. Before this patient’s episode, he had two prior GBS flares, each precipitated by a viral infection followed by complete recovery besides intermittent paresthesias. We also consider the nosology of this illness in the spectrum of rGBS and Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), with their differing natural histories, prognosis, and therapeutic approaches. For patients who have a history of inflammatory demyelinating polyradiculopathies who develop COVID-19, we recommend close observation for neurologic symptoms over the next days and weeks. Keywords: SARS-CoV-2 neurological complications; recurrent Guillain–BarreÃ�? syndrome; para- infectious Guillain–BarreÃ�? syndrome; Chronic Inflammatory Demyelinating Neuropathy; demyelinating polyradiculopathies.