Crossing barriers for improved outcomes in cancer nanomedicine

Joint Event on 12^th International Conference and Exhibition on Materials Science and Chemistry & 30^th World Nano Conference

May 20-22, 2019 Zurich, Switzerland

B. Devika Chithrani

University of Victoria, Canada

Posters & Accepted Abstracts: J Material Sci Eng

Abstract :

In the battle against cancer, surgery, radiation and chemotherapy remain as the most widely used treatment options. Despite recent progress in conventional methods, there is still an immense need for new treatments that can eradicate cancerous cells while causing much less damage to the healthy tissue. Introduction of high atomic number materials such gold nanoparticles within the tumor could enhance the local radiation dose while minimizing the damage to surrounding tissue. In addition to this, NP-based technology has the capability to develop novel multiplex systems to combine more than one treatment modality for creating a more aggressive and effective approach in eradicating cancer. However, consideration of all three interfaces: in vivo delivery, tissue penetration, and successful delivery to individual tumor cells can play a bigger role in their future success. It is known that in vitro data cannot be extrapolated directly to in vivo or clinical settings. I will discuss how we can use gold nanoparticle as a model nanoparticle system to improve the bio-nano interface for improved outcome in cancer therapy at this conference.