Development and evaluation of digestive enzyme formulations

3^rd International Conference and Exhibition on Biowaivers, Biologics & Biosimilars

October 27-29, 2014 Hyderabad International Convention Centre, Hyderabad, India

Chaudhari Nilesh B, Chavhan Vinita Singh, Chaudhary Sarita A and Kazi Aasim A

Posters: J Bioanal Biomed

Abstract :

Enzymes are proteins that facilitate chemical reactions in living organisms. In fact, they are required for every single chemical action that takes place in our body. All of our cells, organs, bones, muscles, and tissues are run by enzymes. Digestive enzyme deficiency is major concern in older age group. Cooking process inactivates almost all enzymes at 118- 129°C, so causes high stress to endocrine system. Enlargement of pancreases & pituitary gland is major concern in America. Pepsin is a proteolytic enzyme which breaks the protein into the small polypeptide chain. Pepsin causes breakdown of protein having aromatic ring. Agar beads of pepsin have shown good spherical shape, % entrapment efficiency and % drug release. So to decrease the stress level on the endocrine system it is important to take enzyme supplementation daily. Present article is presentation of development of such formulations and is a attempt to make health care cost effective by indirect way as supplementation of enzyme leads to long & healthy life.

Biography :

Chaudhari Nilesh B is postgraduate in pharmaceutics from Padmashree Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pune. He completed graduation in the year of 2011 from NDMVP's College of Pharmacy, Nashik. He is winner of intercollegiate poster presentation competition organized by University of Pune.