Faluyi Oyetayo Bolanle
Federal University of Technology, Nigeria
Posters & Accepted Abstracts: J Veterinar Sci Techno
Until recently most studies overlooked the potential role of vitamins in optimizing immune response in chickens, particularly in response to infections from bacteria and viruses. Vitamins-A, D and E have been demonstrated to have a direct modulating activity on the immune system. This study was therefore carried out to determine the effect of varying vitamin-A supplementary levels in diets of broiler chickens on immunological response to Newcastle Disease Vaccinations (NDV). A feeding trial was conducted using 120 day old broiler chicks divided into 3 treatments with 4 replicates of 10 birds each. Birds in treatment-A served as the control group and fed diets containing the National Research Council requirement level of vitamin-A; birds in treatment-B and C were fed diets supplemented with 100 and 200 mg/kg of dietary vitamin-A respectively throughout the study. Hemagglutination Inhibition (HI) test performed on serum samples from experimental chickens assessed humoral immunity as antibody production to NDV. The results showed that the immunological responses after vaccination with NDV Hitchner B1 strain revealed that chickens fed either 100 or 200 mg/kg of vitamin-A recorded the highest antibody titer (log27) while those fed the control diet had the lowest antibody titer (log26). Administration of NDV LaSota vaccines elicited higher antibody titer (log29) in birds fed 200 mg/kg vitamin-A which was significantly different (P<0.05) from that of birds fed the control diet (log27). It can be concluded that immune response of birds to vitamin-A activity improved with higher supplementary levels.
Email: faluyi2005@yahoo.com
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