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Early detection of ovarian cancer
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Cancer Science & Therapy

ISSN: 1948-5956

Open Access

Early detection of ovarian cancer


JOINT EVENT:25th World Congress on CANCER SCIENCE AND THERAPY & 10th World Congress on BIOMARKERS & CLINICAL RESEARCH

October 18-20, 2017 Baltimore, USA

Tijen Atacag

Near East University, Turkey

Scientific Tracks Abstracts: J Cancer Sci Ther

Abstract :

Many cancer patients are in a hypercoagulable state. The association between thrombocytosis and the presence of an underlying solid tumor has long been recognized, prompting investigation of the role of platelets in disease progression. The pathogenesis of the hypercoagulable state of malignancy involves the interplay of multiple variables. Thrombotic episodes may precede the diagnosis of malignancy by months or years. In gynecologic cancers, pre-operative elevations in platelet counts have been described for endometrial, vulvar and cervical cancer and studies suggest that thrombocytosis may be an independent poor prognostic factor in locally advanced cervical carcinomas. The recent studies indicate that platelets are actively involved in tumour growth and metastasis, especially in ovarian cancer. Ovarian cancer is the deadliest gynecologic malignancy. Early detection decreases the mortality. But, because of the anatomic location within the peritoneal cavity, ovarian cancer may be very advanced or even distantly metastatic before a patient experiences symptoms. Further, these symptoms are often initially vague and non-specific, and may mimic a variety of benign conditions. Platelet count is an easy and cheap parameter. It can be done everywhere. Thrombocytosis can help us in the differential diagnosis of adnexal masses especially if combined with CA-125. The aim of this present paper is to emphasize that thrombocytosis when combined with CA-125 can be used as an early detection parameter in the diagnostic evaluation of suspicious pelvic masses.

Biography :

Tijen Atacag is associated with Near East University, Turkey.

Google Scholar citation report
Citations: 3968

Cancer Science & Therapy received 3968 citations as per Google Scholar report

Cancer Science & Therapy peer review process verified at publons

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