Effect of kisspeptin-10 on serum testosterone levels in stallion, donkey and mule

6^th Global Veterinary Summit

November 14-16, 2016 Atlanta, USA

Irfan Zia Qureshi and Rana Waseem Akhtar

Quaid-i-Azam University, Pakistan

Posters & Accepted Abstracts: J Vet Sci Technol

Abstract :

This study was conducted to determine the response of serum testosterone in male equines following bolus doses of Kisspeptin, hCG and LH. Male animals of each equine species (stallions, donkeys and mules) were divided into four groups. Kisspeptin -10 was administered intravenously into the jugular vein of all animals. Group-1: Treated with 3 ml (0.95% saline); Group-2: Treated with 50 �¼g Kisspeptin; Group-3: Treated with 2500 IU hCG and, Group-4 treated with 400 �¼g LH. Serum testosterone levels among different treatment groups were compared through one way ANOVA, P<0.05 was taken as significant difference. Administration of Kisspeptin to all the three species i.e., stallions, donkeys and mules led to significant (P<0.001) increase in testosterone concentration at 240 min post dose as compared to the saline treated group. Upon LH administration a highly significant increase (P<0.001) in serum testosterone concentrations was noticeable at 240 min in stallions, donkeys and mules as compared to pre dose testosterone concentrations. In case of hCG treatment, the concentration of serum testosterone was also found significantly greater in stallions (P<0.05), in donkeys (P<0.01) and in mules (P<0.001) at 240 min post dose as compared to the pre-dose concentration. Administration of Kisspeptin and other reproduction related hormones to male equines causes significant increase in serum testosterone concentration demonstrating similar effect of all the peptides.

Biography :

Email: irfanziaqureshi@gmail.com