Shu-Lin Lee and Shu-Cheng Tsai
Chung Chou University of Science and Technology, Taiwan
Posters & Accepted Abstracts: J Health Med Informat
Curcumin is a major component of turmeric and is commonly used as a spice and food-coloring agent. The
desirable preventive or putative therapeutic properties of curcumin in animal studies have been considered to
be associated with its antioxidant capacity and protective effect on exercise induced muscle damage. The purpose
of this study was to investigate the effects of curcumin supplementation on muscle mass, muscle damage, and
anti-oxidant in sarcopenia elderly. Subjects required to receive 8 weeks of curcumin supplementation and exercise
training, before and after 8 weeks completion of the body composition, functional fitness, blood anti-oxidation and
anti-inflammatory marker of the test.
Results: There was not improvement in muscle mass and functional fitness after 8 weeks intervention, while the
activity of antioxidant enzymes SOD, GPx, and Catalase increased, but there was not significant difference between
before and after intervention. Muscle damage marker LDH after intervention was significantly lower than before
intervention (p <0.05). The above results showed that 8 weeks curcumin supplemented with exercise training can
significantly improve the muscle damage.
Recent Publications
1. Bowen, T.S., Schuler, G., & Adams, V. (2015). Skeletal muscle wasting in cachexia and sarcopenia: molecular
pathophysiology and impact of exercise training. J Cachexia Sarcopenia Muscle, 6(3), 197-207.
2. He, Y., Yue, Y., Zheng, X., Zhang, K., Chen, S., & Du, Z. (2015). Curcumin, inflammation, and chronic diseases:
how are they linked? Molecules, 20(5), 9183-213.
3. Jin, B. & Li, Y.P. (2007). Curcumin prevents lipopolysaccharide-induced atrogin-1/MAFbx upregulation and
muscle mass loss. Journal of Cellular Biochemistry, 100(4), 960-9.
4. Joseph, A.M., Adhihetty, P.J., & Leeuwenburgh, C. (2016). Beneficial effects of exercise on age-related
mitochondrial dysfunction and oxidative stress in skeletal muscle. Journal of Physiology, 594(18), 5105-5123.
5. Zdzieblik, D., Oesser, S., Baumstark, M.W., Gollhofer, A., & Konig, D. (2015). Collagen peptide supplementation
in combination with resistance training improves body composition and increases muscle strength in elderly
sarcopenic men: a randomised controlled trial. British Journal of Nutrition, 114(8), 1237-45
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