Luciene Covolan
Universidade Federal de Sao Paulo, Brazil
Keynote: J Neurol Disord
Deep brain stimulation (DBS) has been proposed as an alternative treatment for patients with epilepsy who are refractory to conventional treatment. There is a consensus that high frequency stimulation of the anterior nucleus of thalamus (ANT) is capable to reduce seizure frequency. Our group has focused on studies of ANT DBS in pilocarpine model of temporal lobe epilepsy. Here, I�ll present the data relative to the effects of ANT DBS in the acute and chronic phases of this rodent model, focusing in some interesting aspects of hippocampal excitabilitiy, plasticity, neuroprotection and spatial memory.
Neurological Disorders received 1343 citations as per Google Scholar report
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