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Enantioselective total synthesis of biologically active natural products
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Medicinal Chemistry

ISSN: 2161-0444

Open Access

Enantioselective total synthesis of biologically active natural products


18th International Conference on Medicinal Chemistry & Targeted Drug Delivery

December 06-08, 2017 Dallas, USA

Suraksha Gahalawat

Thapar University, India

Posters & Accepted Abstracts: Med Chem (Los Angeles)

Abstract :

Natural products have been the most significant source of drugs and drug leads in history. Asymmetric synthesis of natural product is a key process in modern chemistry and is particularly important in the field of pharmaceuticals, as the different enantiomers or diastereomers of a molecule often have different biological activity. The ultimate goal of organic synthesis is to assemble a given organic compound from readily available starting materials and reagents in a highly efficient way. Among an array of naturally occurring and biologically important compounds, the functionalized amino acids, 2-alkyl substituted tetrahydroquinolines, endocannabinoid lipids, 2,5-disubstituted-3-oxygenated THF motifs and cyclodepsipeptides occupy prominent positions. We have recently synthesized medicinally important (+)-serinolamide A, marine natural product (+)-petromyroxol, anti-malarial agent (+)-angustureine and novel macrocycle, haliclamide

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