Evaluation of anti-nociceptive activity of aqueous extract of root of ricinus communis linn on albino rats

2^nd International Conference and Exhibition on Pharmaceutical Regulatory Affairs

November 23-24, 2012 Hyderabad International Convention Centre, India

Sayequa Samreen and T. Jayasree

Posters: Pharmaceut Reg Affairs

Abstract :

Evaluation of Anti-nociceptive activity of aqueous extract of root of Ricinus communis linn on albino rats. The castor oil plant, Ricinus communis, is a species of flowering plant in the spurge family, Euphorbiaceae. It belongs to a monotypic genus, Ricinus, and subtribe, Ricininae. Water extract of root has showed some analgesic activity in rats. It also has anti-inflammatory and anti-histaminic properties. These properties are speculated to the presence of ricinoleic acid, dihydroxystearic, linoleic, oleic, stearic acids, beta-sitosterol, catalase, peroxidase, and reductase. Materials used are, Aqueous extract of root of Ricinus communis (AERRC), Soxhlet?s apparatus for extraction, Albino rats, Tail clip, Standard drug: Aspirin. Five groups of albino rats will be taken each consisting of five animals. Group-I will be taken as control to which normal saline will be given, Group-II standard drug will be given, Aspirin, Group III, IV, V test drug will be given AERRC(100mg/kg,200mg/kg,400mg/kg). Results will be discussed at the time of presentation.