Evaluation of the role of Ischemia Reversal Therapy in Ischemic Heart Disease using Stress Myocardial Perfusion Imaging: A Pilot Study

5^th World Heart Congress

March 27-28, 2019 Sydney, Australia

Rahul Mandole

Madhavbaug Cardiac Care Clinics and Hospital, India

Scientific Tracks Abstracts: J Cardiovasc Dis Diagn

Abstract :

Ischemic heart disease(IHD) incidence has increased in India. Ayurveda, a 3000-year-old Indian traditional medicine system along with allopathic medicine can provide a solution to improve myocardial perfusion in stable IHD patients. This pilot study involves Ischemia Reversal Programme(IRP), an Ayurvedic treatment modality to aid IHD patients using SPECT-myocardial perfusion imaging(SPECTâ??MPI) for assessment of myocardial perfusion in IHD patients. The present open-label study involved fourteen IHD patients who underwent IRP(total 21 sittings, administered twice per week) in Madhavbaug clinics along with their standard care therapy. The inclusion criteria were patients with known IHD, age= 40-70yrs, BMI >20kg/ m2, and stress test positive for inducible ischemia. SPECT-MPI was performed at enrolment and post- IRP(12-week follow-up) from December 2016-September 2017.VO2max and time to onset of ischemia after stress test were also recorded. Seattle Angina Questionnaire(SAQ) was telephonically completed by research coordinators.Observations from SPECT-MPI test showed a significant difference in Summed Stress Score[SSS] (13.5 ± 10.3, baseline vs. 10.7 ± 10.1, post-IRP; p=0.01) as well as Summed Difference Score[SDS] (8.9 ± 6.2, baseline vs. 6.2 ± 6.3, post- IRP; p=0.03) compared from baseline to post-IRP sittings. And we also observed increase in VO2max levels(12.8 ± 5.7 to 19.4 ± 7.8) and time to onset of ischemia(370.7 ± 201.1 to 597.8 ± 201.9) was observed. SAQ scores showed significant improvement post-IRP(30.2± 3.6 to 32.7± 3.5). Findings of this study suggest an improvement in myocardial perfusion post-IRP in IHD patients and depicts the positive role of IRP as an add-on to standard care therapy in IHD management.

Biography :

Rahul Mandole is an eminent researcher in the field of multidisciplinary clinical cardiology. Dr Rahul has completed his graduation in Ayurveda medicines and master’s in clinical research. He has presented more than 20 novel research presentation at global cardiology conferences that includes World Cardiology Congress, European society of Cardiology Heart Failure Conference and Cardiology Society of India’s Annual Cardiology Meet. Dr Rahul Mandole is author of 9 research articles which have been published peer reviewed indexed journals.