Florea Mihai-Alexandru
University of Medicine and Pharmacy, Romania
Scientific Tracks Abstracts: Med Chem (Los Angeles)
The extraction of oil from raw material of different origins by applying green technologies is a topical concern. Solvent extraction, hydraulic pressing or heat based procedures should be replaced by clean technologies, such as enzymatic hydrolysis, microwave or ultrasonic assisted extractions, or supercritical fluid extraction using CO2. The aim of laboratory study was to test and evaluate three alternatives procedures for extracting oil from small marine fish raw material, versus a classical Soxhlet extraction, as a control method. The homogenized sample was extracted in three replicates and the applied procedures were: repeated washing with water of raw material and oil separation by centrifugation (RMW-C), oil separation by centrifugation (RMC), centrifugation followed by repeated water washing of the separated oil, until neutral pH is reached (RMS-W). In order to evaluate the oil quality, the chromatographic profile of fatty acids was analyzed. Considering Soxhlet extraction as reference, by which it yields 62,9% oil, all tested procedures have a lower extraction efficiency, the most valuable being RMC with an yield of 72% oil from reference value. For all tested procedures, the chromatographic analysis showed similar composition in fatty acids profiles, the values for polyunsaturated fatty acids being approximately 7% higher for solvent-free extractions, compared to Soxhlet method. The sum of eicosapentaenoic (EPA) and docosapentaenoic (DHA) acids has overall average values of 30% that fall within the official quality indicators of fish oils, used in Nutraceuticals application. Preliminary results show that solvent-free extraction should be considered as a valuable option for fish oil extraction.
Florea Mihai-Alexandru has completed his Master degree at the age of 24 years at Bucharest University. In the present he is chemist researcher at Biotehnos R&D department and PhD student at University of Medicine and Pharmacy „Carol Davila”, Bucharest, Romania. He was a member in research teams at two national project and published 2 papers in reputed journals.
Medicinal Chemistry received 6627 citations as per Google Scholar report