Subhashree Sarangi, A P K Mahapatra, A K Kundu and S Mohapatra
Orissa University of Agriculture & Technology, India
Posters-Accepted Abstracts: J Vet Sci Technol
The ability to engineer transgenic animals i.e., animals that carry a foreign gene that has been deliberately inserted into their genome is possible due to accelerated breakthroughs in molecular biology. Though the majority of transgenic animals produced so far are mice, the technology has also produced rats, rabbits, pigs, sheep and cows. There are many applications of transgenic models in biomedical research. Interestingly, the creation of transgenic animals has resulted in a shift in the use of laboratory animals from the use of higher-order species such as dogs to lower-order species such as mice and has decreased the number of animals used in such experimentation especially in the development of disease models. This is certainly a good turn of events since transgenic technology holds great potential in many fields including agriculture, medicine and industry. These animals illustrate the in vivo extension of recombinant DNA technology for the study of specific molecules in diseases and for the production of animal models that can lead to the discovery of new treatments.
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