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Glycated hemoglobin (hba1c) levels in non-diabetic patients as early indicator of coronary disease. Experience of regional hospital
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Journal of Interventional and General Cardiology

ISSN: 2684-4591

Open Access

Glycated hemoglobin (hba1c) levels in non-diabetic patients as early indicator of coronary disease. Experience of regional hospital


10th World Heart Congress

August 23-24, 2021 | Webinar

V.Vasilakopoulos

Kozani General Hospital, Greece

Scientific Tracks Abstracts: jigc

Abstract :

Purpose: Diabetes is a strong risk factor for cardiovascular disease. Prediabetes (Glu: 110-126mg / dl) is fi ve times more likely to progress to Diabetes Mellitus (DM). According to the guidelines of the World Health Organization, the diagnosis of diabetes requires a glycosylated hemoglobin (HbA1c) value greater than 6.4%. This study was designed to investigate the relationship between HbA1c and coronary artery disease (CAD), as well as the relationship between HbA1c and the ultrasound markers of patients under study. Material-Method: 69 participants (35% women, 65% men), aged 25 to 79 years without diagnosis of MD based on fasting glucose measurements (Glu: <110mg / dl), who did not receive anti-diabetic medication, were recorded. The participants were divided into 2 groups. The fi rst group (n = 29) with HbA1c value from 5.5% to 6.4% while the second group (n = 40) with HbA1c value ≤5.5%. Results: In the 1st group, CAD was found at 49.6%, while in the second group the corresponding percentage of CAD was found at 28.5% with a statistically signifi cant correlation. No statistically signifi cant difference was observed in the ultrasound indices of the two study groups [mean Simpson ejection fraction (EF) 55.3% vs 50.43%, mean left ventricular diastolic diameter (LVEDD) 49.62 mm vs 48.15mm, mean left atrium diameter (LAd) 38.2mm vs 39.6mm]. Conclusions: In conclusion, the group with HbA1c values of 5.5% -6.4% showed CAD at a rate of 21% higher compared to the group with HbA1c ≤5,5%. The ultrasound indices studied did not show statistically signifi cant differences between the two groups, which means that they do not help to predict coronary heart disease in the groups with the specifi c HbA1c levels.

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Citations: 11

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Journal of Interventional and General Cardiology peer review process verified at publons

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