Manuela Stoicescu
University of Oradea, Romania
Scientific Tracks Abstracts: J Cardiovasc Dis Diagn
Objective: The most important objective of this presentation is to put into the discussion this important topic of the hormonal
therapy replacement if really protect a woman against heart attack? We know that a woman is naturally protected from
estrogenic hormones during her period of menstrual cycles against atherosclerosis, ischemic cardiopathy, and myocardial
infarction. During menopause, because menstrual cycles disappear the womanâ??s lost the protection of estrogens hormones for
atherosclerosis, ischemic heart disease and the risk of heart attack become high. For this reason, the hope appears from the
hormonal therapy replacement after menopause, which develops the idea that if a woman follows the therapy with estrogens
hormones or a combination between estrogens and progesterone hormones will be possible to protect against atherosclerosis,
ischemic heart disease, and heart attack. The most important question is that this therapy is really safe and with benefits for
the womanâ??s patients?
Material and Methods: Present the situation of a woman patient, in menopause from four years ago, when started the
estrogens hormonal therapy replacement with Estradiol 1 pill/day. After this period of time, she came at the consultation with
constrictive chest pain as a claw, 10 minutes duration, which stopped immediately after 1 drug of nitroglycerin administration
under the tongue. The EKG registered during crises of chest pain shown ischemic lesion changes in anterior leads. Also, the
patient presented the apparition of a nodule in the left breast. This appears after hormonal therapy replacement.
Results and Discussions: The most important question persist: deserve a woman during menopause to follow the hormonal
therapy replacement for protection against atherosclerosis and ischemic heart disease? The presentation of this case shows, that
the ischemic heart disease appears under estrogens therapy replacement and more than that, dangerous side effects appearsâ??
nodule inside of the left breast.
Conclusion: The most important conclusion of this presentation is that the hormonal therapy replacement started with all
good intentions for the womanâ??s patients isnâ??t safe, because the evolution of atherosclerosis process persist and ischemic heart
disease advance during this therapy and more than that with price of dangerous side effects-like apparition of a nodule in the
breast. The practice proved that the therapy isnâ??t safe.
Manuela Stoicescu, Consultant Internal Medicine, Doctor (PhD in Internal Medicine), is Assistant Professor of Medical Disciplines Department, University of Oradea. She is a Faculty of Medicine and Pharmacy, Romania, Internal Medicine Hospital and Office. She is Member of Romanian Society of Internal Medicine, Member of Romanian Society of Cardiology, Chemistry, Biochemistry and Member of Balcanic Society of Medicine. She was invited as a speaker at 24 International Conferences.
E-mail: manuela_stoicescu@yahoo.com
Cardiovascular Diseases & Diagnosis received 427 citations as per Google Scholar report