Intraoperative radiotherapy for breast cancer

World Congress on Breast Cancer

August 03-05, 2015 Birmingham, UK

Roland Reitsamer

Paracelsus Medical University Salzburg, Austria

Posters-Accepted Abstracts: J Cancer Sci Ther

Abstract :

Intraoperative radiotherapy (IORT) is referred to the delivery of a single high dose of irradiation directly to the tumor bed during surgery. Variable techniques (application of electrons, soft x-ray application) and different therapeutic approaches (IORT in boost modality, accelerated partial breast irradiation) are under investigation. The different techniques are presented and discussed. The results of the ELIOT trial and the TARGIT trial are discussed as well as the 10-year results of IOERT (intraoperative electron radiotherapy) in boost modality and the ISIORT pooled analysis on 1100 patients treated in boost modality combined with whole breast irradiation. Additionally, data on IOERT in patients after neo-adjuvant chemotherapy and in triple- negative patients are presented. Future aspects of IORT will be addressed finally.