Magnetic resonance imaging in multiple sclerosis: The relevance of brain atrophy in MS

4^th International Conference on Nursing & Healthcare

October 05-07, 2015 San Francisco, USA

Kerstin Bendfeldt

University Hospital Basel, Switzerland

Posters-Accepted Abstracts: J Nurs Care

Abstract :

Multiple Sclerosis (MS) is an inflammatory and neurodegenerative disease which is associated with marked brain atrophy. The magnetic resonance imaging (MRI) is a means of predicting subsequent disability. Brain atrophy occurs early in MS, progresses throughout the course of the disease and affects both gray matter and white matter. Advances in MRI techniques and image processing software improve data quality and allow new outcome measures such as whole brain and local atrophy measurements with acceptable processing times. Measurements of brain atrophy are likely to play an increasing role in MS research and in the diagnosis and staging of the disease. The talk will give an overview on the analysis methodology/software available to study structural changes related to brain atrophy in MR images. In addition, it will be discussed how cortical and deep gray matter atrophy in MS is related to neurodegeneration and how this eventually could lead to clinical and to cognitive problems in relapsing and progressive MS. The talk will also include topics as the relevance of brain volume and atrophy quantification in the context of new emerging treatments and clinical trials. Special emphasis will be placed on multivariate classification techniques which are a promising way to assist in early detection of neurodegenerative brain diseases.

Biography :

Email: kerstin.bendfeldt@unibas.ch