Model-based optimization of lignocellulosic bioprocesses for efficient production of biofuel

4^th International Conference on Bioprocess and Bio Therapeutics

October 20-21, 2016 Houston, USA

Pornkamol Unrean

National Center for Genetic Engineering and Biotechnology-NSTDA, Thailand

Posters & Accepted Abstracts: J Bioproces Biotechniq

Abstract :

The utilization of lignocellulosic biomass feedstock for bio-based processes is expected to contribute substantially to the future supply of fuels, chemicals and materials serving bio-based economy. We have developed modeling approach to describe cellconsortium and simultaneous saccharification and fermentation (SSF) of lignocellulose-based processes. The modeling tool is useful for rapid process design and optimization to meet the technical and economic requirement of industrial-scale lignocellulosic processes. To demonstrate the model-based approach, we have utilized the modeling for optimizing lignocellulosic ethanol production. The predicted fermentation kinetics and ethanol production performance agreed well with the experimental results, thus validating the model. By using model-based design of feeding profiles for substrate and yeast cell in fed-batch SSF process, an efficient ethanol production with high ethanol titer and yield was accomplished. The cell-consortium kinetic model was also applied to design optimal cell ratio for efficient conversion of biomass feedstock to ethanol at improving titer and productivity. The modeling is, therefore, considered as a promising approach for rapid optimization of efficient and sustainable production of bioproducts from lignocellulosic biomass.

Biography :

Email: pornkamol.unr@biotec.or.th