Novel drug delivery in herbal medicines

International Conference and Exhibition on Traditional & Alternative Medicine

December 09-11, 2013 Radisson Blu Plaza Hotel, Hyderabad, India

Mukesh Singh Sikarwar

Accepted Abstracts: Altern Integ Med

Abstract :

Herbal medicines have widely been used all over the world since time immemorial. In recent years, there was unprecedented development in herbal medicines as they gain popularity in the developed world. Recently there was a greater global interest in non-synthetic, natural drugs derived from plant/herbal sources due to better tolerance and minimum adverse drug reactions. Plants have been used in a wide variety of dosage form. Traditional dosage form includes pill, powder, semi fluid extract, tincture, decoction, medicated tea, solutions and many other traditional/alternative systems of medicine dosage forms. In past, novel drug delivery approaches were not applied to herbal medicines owing to lack of scientific validation and processing difficulties, such as adulteration, standardization, extraction, purification and identification of marker compounds in complex poly-herbal dosage form. In present scenario, due to advancement in interdisciplinary sciences and novel strategy in isolation, purification and identification techniques the variety of novel herbal formulations like polymeric herbal nano-carriers, phytosomes, Herbosomes, pro-niosomes, nanoemulsions, microsphere, transferosomes, implants and ethosomes has been reported using bioactive plant extracts/phytoconstituents. These novel formulations were found to have remarkable advantages over conventional formulations of plant origin such as enhancement of solubility, bioavailability, reduced toxicity, improved pharmacological activity, better stability, sustained delivery, and protection from physical and chemical degradation. Recently, many formulations based on novel drug delivery system are produced by patented/non-patented technology from various herbal drugs/phytoconstituents such as curcumin, quercetin, silybin, bilobalide, marsupsin, andrographolide, coumestans, metrine, embelin, brucine, rutin, apigenin, luteolin and many more. Hence novel drug delivery in herbal medicines has become a tool to improve herbal medicine pharmacokinetic and pharmacodynamic profile in order to improve its safety and efficacy.

Biography :

Mukesh Singh Sikarwar has completed his Ph.D. at the age of 32 years from KLE University, Belgaum, Karnataka, Accredited A Grade by NAAC placed in category A by MHRD (GoI). He is working as Assistant Professor in Department of Pharmacognosy, KLEU College of Pharmacy, Belgaum a constituent college of KLE University. He has published 43 research and review papers in various peer reviewed internationals and national journals and serving as reviewer for many international journals. He has 7 years teaching and research experience. He has presented 22 research papers in various national and international conferences. He is a life member of APTI, annual member of ISPE and registered as pharmacist with M. P. State Pharmacy Council.