Low Wei Xiang Alvin
Singapore General Hospital, Singapore
Posters & Accepted Abstracts: J Cancer Sci Ther
This study evaluates the oncological outcomes of RARP in a multiracial Asian population from a single institution. All suitable patients from 1st January 2003-30th June 2013 were identified from a prospectively maintained cancer registry. Peri-operative and oncological outcomes were analyzed. Significance was defined as p<0.05. There were n=725 patients identified with a mean follow-up duration 28 months. The mean operative time, EBL and LOS were 186 min, 215 ml and 3 days, respectively. The pathological stage was pT2 in 68.6% (n=497/725), pT3 in 31.3% (n=227/725) and n=1 patient with pT4 disease. The pathological Gleason scores (GS) were 6 in 27.9 % (n=202/725), GS 7 in 63.6 % (n=461/725) and GS�8 in 8.0% (n=58/725). The node positivity rate was 5.8 % (n=21/360). The positive margin rates were 31.0% (n=154/497) and 70.9 % (n=161/227) for pT2 and pT3, respectively and decreasing PSM rates are observed with surgical maturity. The biochemical recurrence rates were 9.7% (n=48/497) and 34.2% (n=78/228) for pT2 and pT3/T4, respectively. On multivariate analysis, independent predictors of BCR were pathological T-stage and pathological Gleason score. Post-operatively, 78.5% (n=569/725) of patients had no complications and 17.7% (n=128/725) had minor (Clavien grade I-II) complications. This series, representing the largest from Southeast Asia suggests that RARP can be a safe and oncologically feasible treatment for localized prostate cancer in an institution with moderate workload.
Email: alvinlwx@gmail.com
Cancer Science & Therapy received 3968 citations as per Google Scholar report