One-stage penectomy and phalloplasty for squamous cell carcinoma of the penis in a 42-year-old male

International Conference on Prostate Cancer

June 22-24, 2015 Florida, USA

Salgado C J, Sputova K, Horesh E, Manfrini D and Kava B

Posters-Accepted Abstracts: J Cancer Sci Ther

Abstract :

Penile squamous cell carcinoma is a relatively rare malignancy in most developed nations, accounting for less than 1% of all cancers in men in the US. The majority of primary tumors originate distally on the glans or prepuce, with a minority on the coronal sulcus or shaft. Most glandular and preputial carcinomas can be treated with organ-sparing techniques to maintain functional penis for urination and intercourse. However, total penile amputation is indicated for tumors whose size or location would not permit excision with an adequate surgical margin. According to European guidelines, a total phallic reconstruction should be offered to patients undergoing total amputation. However, reconstruction is usually delayed months to years following penile amputation despite the mutilating character of this kind of surgery, which results in significant negative effects on patientâ??s quality of life, wellbeing, and psychological health. Studies have shown pathological anxiety in more than 30%, mental illness in over 50%, avoidance behavior in over 25%, and impaired well-being in over 40% of patients. Almost half of patients in an additional study suffered from post-traumatic stress disorder. Another study reported that out of 29 patients treated with penectomy, one committed suicide and another had a failed suicide attempt.We present a 42-year-old man with a history of multiple squamous cell carcinomas of the penis who presented to us with progression of high-grade carcinoma of the penis for definitive treatment. This case report demonstrates the safety, well-tolerated oncologic outcome, and improvement in patient quality of lifeof performing immediate phallic reconstruction following radical penectomy.