Pharmacological activities of Moringa oleifera in topical formulations

International Conference and Exhibition on Marine Drugs and Natural Products

July 25-27, 2016 Melbourne, Australia

Thalles Yuri Loiola Vasconcelos, Italo Mendes Cangussu, Raphael Lucas de Vasconcelos Saraiva, Debora Patricia Feitosa Medeiros and Aristides Avilo do Nascimento

Superior Institute of Applied Theology, Brazil

Posters & Accepted Abstracts: J Pharmacogn Nat Prod

Abstract :

Moringa (Moringa oleifera) is a widely adapted plant that is used as a medicinal herb, is already recorded since 2000 years B.C. The Moringa oleifera is a natural plant of the Indian northwest, widely distributed not only in India but in the Philippines, Egypt, Thailand, Ceylon, Burma, Malaysia, Singapore, Pakistan, Nigeria and Jamaica. Moringa is a plant having potential for producing various products for topical application. This species has antimicrobial activity against several human pathogens, including Gramnegative: Shigella shinga, Pseudomonas aeruginosa, S. sonnei and Pseudomonas spp. and also against Gram-positive: Staphylococcus aureus, Bacillus cereus, B-hemolytic Streptococcus, Bacillus subtilis, Sarcina lutea and Bacillus megaterium. This effect can be observed in different parts of the plant such as leaves, flowers, seeds, roots and fruit peel. In addition to the bactericidal effect, the aqueous extract of leaves of Moringa oleifera has anti-inflammatory, analgesic, rejuvenating and antioxidant activity. The extract of pulp and seeds of Moringa has healing action, activity attributed to the high content of protein, zinc and anti-microbial components present in Moringa. The healing activity of Moringa oleifera is able to overcome the healing suppression action of dexamethasone. Moringa seeds also have photoprotective activity, being considered an active sunscreen that can be incorporated into other formulations to provide an increase in photoprotection. The presence of flavonoids in Moringa oleifera is reason to encourage researchers to evaluate their potential sunscreen. Thus, several topical formulations can be prepared from the Moringa oleifera as ointments and creams with anti-inflammatory, healing, antimicrobial and even cosmetics with sunscreen and rejuvenating action.

Biography :

Thalles Yuri Loiola Vasconcelos has completed his Bachelor of Pharmacy from the Applied Theology Institute (INTA) in 2015. He is the member of the Academic League of Pharmacology (LACFAR) of INTA Colleges. His experience in research areas includes pharmacotechnique, pharmaceutical technology and quality control for cosmetics and pharmaceuticals. Currently, he is a member of Research Group on Nutrition, Chemical Elements and Molecules (NELMOL), and Postgraduate student in the course of ‘Clinical Pharmacy and Pharmaceutical Care’ in Superior School of Amazon.

Email: yuriloiola@gmail.com