Priapism and clozapine use in a patient with hypochondriacal delusional syndrome

3^rd Global Experts Meeting on Medical Case Reports

May 09-10, 2016 New Orleans, USA

Fabricio Donizete da Costa

State University of Campinas, Brazil

Posters & Accepted Abstracts: J Clin Case Rep

Abstract :

Priapism is a urological emergency that results in a penile or clitoral engorgement, having several triggers by the use of medications, including psychiatric drugs, such as antipsychotics and antidepressants. The most common priapism presentation is the ischemic type that can result in the fibrosis of corporus cavernosus with a significant risk of persistent erectile dysfunction. It is believed that, in the case of antipsychotic use, priapism is mediated by an imbalance in alpha-1 adrenergic blocking with large variation affinity for alpha-1 adrenergic receptors among antipsychotics. This case report contributes to the study of this rare but severe side effect. Priapism can limit both treatment adherence and the reproductive future of our patients. We describe a case report of a patient with a delusional hypochondriac syndrome who had multiple priapism episodes using clozapine 50 mg/daily. In conclusion, we make brief comments on priapism management, a hard clinical dilemma. This case report has the purpose to discuss this rare adverse event but very severe, mainly between clinicians and psychiatrists who deal with antipsychotics drugs.

Biography :

Email: psiquiatrista@gmail.com