Primary squamous cell carcinoma of kidney associated with large calculus in non-functioning kidney: A case report

9^th International Conference on Nephrology: Kidney & Therapeutics

September 29-30, 2016 Orlando, USA

Sanjay Kumar

Sawai ManSingh Medical College, India

Posters & Accepted Abstracts: J Nephrol Ther

Abstract :

Primary squamous cell carcinoma (SCC) of renal pelvis is a rare neoplasm, accounting for 0.5-0.8% of malignant renal neoplasm. Risk factors are renal calculi, infection, endogenous and exogenous chemicals, hormonal imbalance, radiotherapy and vitamin A deficiency. SCC of urinary tract is more frequently reported in urinary bladder and male urethara. We report a case of SCC of left renal pelvis associated with long standing large calculus in a 75-years old male who presented with history of chronic dull aching pain in left flank region for last 10 years and has a past history of left pyelolithotomy about 30 years back and no history of hematuria, significant weight loss or fever. General physical examination was unremarkable. All routine blood investigations were normal except serum creatinine (2 mg/dl). NCCT of KUB region was suggestive of large 3.6 cm calculus in left renal pelvis along with large heterogeneous density lesion involving mid and lower pole of the kidney with perinephric fat stranding. DTPA scan was suggestive of left nonfunctioning kidney (GFR-9 mL/min/1.73 m2). He underwent left radical nephrectomy. Histopathological examination of the specimen revealed features of squamous cell carcinoma of renal pelvis with extensive involvement of renal parenchyma. Patient was discharged on day seven and kept on follow up. The patient remained disease free for three months post surgery and was lost to follow up then. So, any patient presenting with long history of renal calculus with solid component in non-functioning kidney, possibility of SCC should always be kept in mind and manage accordingly.

Biography :

Email: sankum10@yahoo.co.in