Protective effects of Boehmeria nivea against oxidative stress in C6 glial cells

3^rd International Conference and Exhibition on Traditional & Alternative Medicine

August 03-05, 2015 Birmingham, UK

Sanghyun Lee1, Xiaoning Wang2, Sunghun Cho1, Sanghoon Yang2, Ho Bang Kim3, Yong-Su Jung4 and Eun Ju Cho1

1Chung-Ang University, Republic of Korea 2Pusan National University, Republic of Korea 3Biomedic Co. Ltd., Republic of Korea 4Yeong-Gwang Agricultural Technology Center, Republic of Korea

Posters-Accepted Abstracts: Altern Integr Med

Abstract :

We investigated 9 kinds of ramie (Boehmeria nivea, (L.) Gaud., Bn; hereafter denoted as Bn) for their protective action against oxidative stress in a cellular system using C6 glial cells. We observed loss of cell viability and high levels of ROS generation after treatment with H2O2 and A�²25-35. However, treatments with Bn extracts led to an increase in cell viability and decreasein ROS production induced by H2O2 and A�²25-35. In particular, the extracts of Bn-02 (seobang variety from Seocheon) and Bn-90 (local variety from Yeonggwang) showed excellent anti-oxidative properties. This indicates that Bn extracts could prevent neurodegeneration by reducing oxidative stress in cells.

Biography :

Sanghyun Lee is currently working as Head of Department of Integrative Plant Science, Chung-Ang University, Korea. In 2003-2005, he was a Research Professor in Biohealth Product Research Center, Inje University, Korea. In 1997-2002, he was a Chief Researcher, Natural Product Research Institute, Seoul National University, Korea. He did his PhD in Seoul National University (Major: Natural Product Chemistry, 1997-2002) Korea, and MS in Kyungpook National University (Major: Medicinal Plant, 1993- 1996) Korea and BS in Kyungpook National University (Major: Agronomy, 1988-1993) Korea..

Email: slee@cau.ac.kr