Asmaa Mahmoud Abdel Magied, Lamiaa Adel Salah Eldin and Emad Salah Eldin Khalaf
Cairo University, Egypt
Posters & Accepted Abstracts: J Cancer Sci Ther
Objective: To evaluate the diagnostic accuracy of adding contrast enhanced spectral digital mammography to the conventional sonomammography in detection of recurrent breast cancer after conservation surgery Patients & Methods: This study included 40 female patients presenting with indeterminate/suspicious breast lump after breast conservative surgery. Their age varied from 34 to 60 years (mean age: 50.3 years). All of the cases (40/40 cases) were subjected to digital mammography and B-mode ultrasonography followed by dual energy contrast enhanced spectral mammography (CESM) within 2 weeks. Results of histo-pathological examinations of surgical or biopsy specimens were obtained and served as the gold standard. Results: The surgical and pathological results of our patients revealed 12/40 (30.0%) benign lesions and 28/40 (70.0%) malignant lesions. The sonomammography results were 18/40 (45.0%) benign lesions (BIRADS 3) and 22/40 (55.0%) malignant lesions (BIRADS 4 and 5). 20 lesions were true positives, 2 lesions were false positive, 8 lesions were false negatives and 10 lesions were true negatives with sensitivity of 71.4% with specificity of 71.4%. The CESM results were 14/40 (35%) benign lesions (BIRADS 3) and 26/40 (65%) malignant lesions (BIRADS 4 and 5). 24 lesions were true positives, 2 lesions were false positive, 10 were true negatives and 4 lesions were false negatives with sensitivity of 85.7% and specificity of 71.4 %. Conclusion: CESM is a promising tool for increasing the sensitivity and the diagnostic accuracy of ultrasound and mammography in follow up of patients with breast conservative surgery.
Email: asmaa_dr79@hotmail.com
Cancer Science & Therapy received 5332 citations as per Google Scholar report
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