Scaffolds and stem cells: A tissue engineering approach

7^th International Conference on Tissue Engineering & Regenerative Medicine

October 02-04, 2017 Barcelona, Spain

Dennis M Lox

Sports & Regenerative Medicine Centers, Florida

Keynote: J Tissue Sci Eng

Abstract :

Regenerative Medicine has found traction in numerous medical specialties, including orthopedic and rheumatologic conditions. Clinical studies have utilized various stem cell sources both allogenic and autologous. Tissue engineering strategies with long routes in wound repair models with a variety of scaffolding materials have been applied to the orthopedic model, most frequently the knee. Scaffolds incorporating stem cell medicine have also been studied and used. The most frequent ailment afflicting the knee is degenerative osteoarthritis. Traditional medical models do not alter the progression of this disorder. It is through investigation of Regenerative and Tissue Engineering strategies, that halting or reversing the progressive nature of degenerative osteoarthritis hope remains. A thorough understanding of the complex nature of degenerative osteoarthritis as a multi-factorial disorder, occurring not only as a result of repetitive stress, joint overload, but also as a function of local cytokine signaling. These signaling processes result in catabolism exceeding reparative processes. These cytokine signaling mechanisms are familiar in the Rheumatologic arena, but have not received widespread attention in mainstream medicine. Stem cells and some scaffolds exert a positive reparative or anabolism to counter the degradation of catabolic inflammatory cytokines. The utilization of scaffolds and stem cells merge Regenerative and Tissue Engineering technologies, where the future may include this as a Preventative Medicine Strategy as well.

Biography :

Dennis M Lox is a world renowned Regenerative Medicine and Stem Cell expert. He has lectured internationally with some of the most acclaimed Regenerative Medicine and Stem Cell researchers in the world. He has a special interest in Regenerative and Stem Cell Medicine relating to athletes, osteoarthritis in athletes and the aging population, and avascular necrosis. He has edited two medical textbooks, written eight medical textbook chapters, and authored numerous scientific publications and abstracts. He maintains an active Regenerative Medicine practice in Beverly Hills, California and the Tampa Bay, Florida area. He has treated patients from around the globe at his offices, ranging from elite professional athletes, to patients in their teens to over age 90. Utilizing his vast experience he maintains an individualized approach to each patient.