Secure accuracy at increased precision of AFM-probe integrated biosensor

7^th Euro Biosensors and Bioelectronics Conference

July 10-11, 2017 Berlin, Germany

Sarmiza Elena Stanca, Matthias Urban, Frank Hantschke, Gabriel Zieger and Wolfgang Fritzsche

Leibniz Institute of Photonic Technology, Germany

Scientific Tracks Abstracts: J Biosens Bioelectron

Abstract :

The plasma membrane regulates the selective interchange of matter between the interior and the exterior of the cell. Understanding this complex process requires knowledge of the plasma membrane�´s molecular constituents. Topical reports prove the access to the molecular level of the synthetic membrane by atomic force microscopy (AFM). This technique also permits an electrochemical investigation in the immediate vicinity of the tip. An electrochemical and topographic study of the living cell membrane, by the mean of an AFM-probe integrated amperometric biosensor is employed to localize specific molecules in the natural cellular membrane (Figure 1). Several materials and shapes of the AFM probes integrated in different systems are presented. It is underlined that the selection of control experiment is decisive in achieving accurate findings. The central concern of this study is how to preserve the sensor response accuracy while increasing its precision.

Biography :

Sarmiza Elena Stanca has her expertise in electrochemical and optical nanosensors achieved during her research activity at the EPFL Lausanne (Swiss Confederation Fellow), UCD Dublin (Marie-Curie-Fellow), UKJ Jena (Marie-Curie-Fellow), University Babes-Bolyai Cluj-Napoca, Research Centre Karlsruhe and IPHT Jena (DAAD Fellow). She is currently a Scientist at the Leibniz Institute of Photonic Technology, Jena.

Email: sarmiza.stanca@leibniz-ipht.de