Shape-shifting 3D protein microstructures with programmable directionality via quantitative nanoscale stiffness modulation

8^th International Conference and Exhibition on Materials Science and Engineering

May 29-31, 2017 Osaka, Japan

Mian Rong Lee

Nanyang Technological University, Singapore

Posters & Accepted Abstracts: J Material Sci Eng

Abstract :

The ability to shape-shift in response to a stimulus increases an organism's survivability in nature. Similarly, man-made dynamic and responsive â�?�?smartâ�? microtechnology is crucial for the advancement of human technology. Here, 10â�?�?30 �?¼m shape-changing 3D BSA protein hydrogel microstructures are fabricated with dynamic, quantitative, directional, and angle-resolved bending via twophoton photolithography. The controlled directional responsiveness is achieved by spatially controlling the cross-linking density of BSA at a nanometer lengthscale. Atomic force microscopy measurements of Young's moduli of structures indicate that increasing the laser writing distance at the z-axis from 100â�?�?500 nm decreases the modulus of the structure. Hence, through nanoscale modulation of the laser writing z-layer distance at the nanoscale, control over the cross-linking density is possible, allowing for the swelling extent of the microstructures to be quantified and controlled with high precision. This method of segmented moduli is applied within a single microstructure for the design of shape-shifting microstructures that exhibit stimulus-induced chirality, as well as for the fabrication of a free-standing 3D microtrap which is able to open and close in response to a pH change.

Biography :

Mian Rong Lee is a final year graduate student from Nanyang Technological University, Singapore. Working with two-photon lasers, she has created protein-based shape-shifting materials, stimuli-responsive actuators and ventured into the direct metal writing of patterned SERS substrates and metamaterials.

Email: mianrong37@gmail.com