Sialic acid, tissue polypeptide antigen, carcinoembryonic antigen in carcinoma of the lung

2^nd World Congress on Cancer Science & Therapy

September 10-12, 2012 Hilton San Antonio Airport, USA

Hoda ali EL-Attar, Zaki AM, EL-Hefni SA ,Mohamad FA, Kandil MH and Abaza MM

AcceptedAbstracts: JCST

Abstract :

Objective:lung cancer, either primary or metastatic is one of the most common malignancies in Egyptian males. Aim: Studying Sialic acid, Tissue, TissuePolypeptide Antigen, Carcino- embryonic Antigen in lung cancer. Material and Methods: 80 male subjects were divided into 4 groups of 20 subjects each as follow: Group1: asymptomatic smokers, Group2: symptomatic smokers, Group3: patients with established lung cancer, Group4: normal healthy controls. To all patients , the following were done: radiography of the chest ,complete urine analysis , CBC ,ESR ,serum levels of:creatinine , calcium and liver profile .Sialic acid,Tissue , TissuePolypeptide Antigen, Carcinoembryonic Antigen were estimated . Statistical analysis were done using SPSS software package version 17 (SPSS, Chicago, IL) .Presentation was in the form of mean and standard deviation. A ?p? value < 0.05 was considered statistically significant. Results: Both Sialic acid and Tissue Polypeptide Antigen in smokers, were increased significantly when each was compared to both controls and asymptomatic smokers and also was significantly higher in patients with lung carcinoma than all the other groups. CEA showed significantly increased level in lung cancer patients compared to the other 3 groups. Conclusion 1-In smokers, tumor markers are in an intermediate position between controls and lung cancer patients. 2-Of the studied tumor markers, sialic acid proved to be the most sensitive in addition to be the easiest to perform in the laborator

Biography :

Hoda ali EL-Attar has completed her MD degree at 2006, published 22papers and work now as a Professor of Chemical Pathology in Medical Research Institute University of Alexandria.