SPECTROPHOTOMETRIC DATA IN THE INTERACTIONS BETWEEN HUMAN IMMUNODEFICIENCY VIRUS (HIV) AND BLOOD CELLS TREATED WITH ANTIRETROVIRAL DRUGS

4^th International Conference on Medical Informatics & Telehealth

October 6-7, 2016 | London, UK

Okwuchukwu Ani and Adaeze Ani

Enugu State University of Science and Technology, Nigeria
Ojukwu University, Nigeria

Posters & Accepted Abstracts: J Health Med Informat

Abstract :

A synergy between engineers and biological researchers may obviously be needed so as to achieve a more reliable research result. The spectrophotometric data on the interactions between the Human immunodeficiency virus (HIV) and blood cells treated with antiretroviral drug were collected to be used to show the effects of antiretroviral drugs on the absorbent characteristics of HIV infected and uninfected blood. The methodology involved the serial dilution of the five different antiretroviral drugs (two HAART/ FDC and three single drugs) and the subsequent incubation with the blood samples collected from ten HIV infected persons that had not yet commenced treatment with the antiretroviral drugs, ten HIV infected persons that had already commenced treatment with the antiretroviral drugs and ten HIV negative persons, for the absorbance measurements using a digital Ultraviolet Visible MetaSpecAE1405031Pro Spectrophotometer. The peak absorbance data for various interacting systems were measured. These were used to show that the antiretroviral drug has the effect of increasing the peak absorbance values of both the infected and uninfected blood components, i.e., the drugs are made able to increase the light absorption capacity of the blood cells. The use of the findings of this work in drug design by pharmaceutical industries may be expected to yield good results.

Biography :

Email: okwyenoch@yahoo.com