Study of antifungal antibiotics on fungi isolated from deteriorating monuments of Madhya Pradesh India

5^th International conference on Probiotics and Prebiotics

June 27, 2022 | Webinar

Vanshree Pandya

Vikram University, India

Scientific Tracks Abstracts: J Exp Food Chem

Abstract :

This study was conducted in order to determine the antifungal activity of the selected antibiotics against the fungal species isolated from various deteriorating monuments of Madhya Pradesh. Fungal species Alternaria sp, Aspergillus flavus, Aspergillus niger, Fusarium sp were isolated from the several monuments of Madhya Pradesh which were in deteriorating condition. Four antibiotics viz., Griseofulvin, Nystatin, Tetracycline and Chloramphenicol were used in different concentrations to study the effect of antibiotics on test fungi. Potato dextrose agar was used as a basal medium and discs of different concentrations of was used in the study. The medium was autoclaved and poured into petri-plates aseptically and allowed to solidify. After which the plates were first inoculated with the test fungal species and incubated at 28oC for 2 days. The antibiotic discs were placed on the medium containing test fungi with the help of sterilised forceps and again incubated at 28oC for 5 days. The zone of inhibition was then measured to test the activity of fungi against the antibiotic. Amongst the four test fungi selected; Aspergillus flavus showed the highest zone of inhibition for each selected antibiotic. Following which Aspergillus niger, and Fusaruim sp. also showed inhibition activity. Alternaria sp showed the maximum zone of inhibition against Griseofulvin antibiotic. The results showed that each test fungi showed zone of inhibition for each antibiotic used. Thus it can be concluded that antibiotics have potential antifungal properties. This can be used as an effective measure to prevent the growth of fungal species on deteriorating monuments of Madhya Pradesh. Keywords: Antibiotics, Fungi, Zone of Inhibition, Monuments, Deterioration.

Biography :

Vanshree is a research scholar at school of studies in microbiology, Vikram University, Ujjain, Madhya Pradesh India. She pursued her Post-Graduation MSc in microbiology from Vikram University, Ujjain. She completed her graduation in BSc in microbiology from future Vision College, Ujjain. She completed her high school 12th from St. Paul’s Convent School, Ujjain. She completed her secondary school 10th from St. Paul’s Convent School Madhya Pradesh. She is currently pursuing PhD from Ujjain Madhya Pradesh on fungi, deteriorating the ancient monuments of Madhya Pradesh India.