Successful completion of pregnancy using apheresis and a balanced dose of coagulation factors in the presence of high thrombophilia and Lp(a) levels in a woman with two previous abortions

5^th Global Nephrologists Annual Meeting

March 31-April 02, 2016 Valencia, Spain

Claas L Neumann, Volker J J Schettler, Egbert G Schulz and Gerrit C Hagenah

Nephrologisches Zentrum Gottingen GbR, Germany

Posters & Accepted Abstracts: J Nephrol Ther

Abstract :

Importance: The case shows clinical impact of thrombophilia and Lp(a) increases in relation to unwanted abortions and a possibility of intervention to allow a successful pregnancy for affected patients. Observations: This is a single case of a 26-year-old woman with two apoplectic insults at young age with different coagulation disorders (type 1 von Willebrand disease, protein S deficiency and increased levels of lipoprotein a) and also strong positive family history. Due to high active thrombophilia status and with respect to very thin coronary arteries a weekly lipoprotein apheresis treatment (LA) was initiated. Before LA was initiated the patient was getting pregnant twice and once under a weekly LA, but lost fetus each time. Under an intensified to treatment intervals twice a week she got again pregnant again. Pregnancy developed regular, without any complications. Baby was delivered in 34th week of pregnancy by caesarean section, developed well and could left the incubator from the 14th day after delivery. Conclusions & Relevance: Under an intensive treatment regimen it was possible to allow a successful pregnancy for high thrombophilia and Lp(a) increased patient. This case shows the importance of an interdisciplinary and individual patientcentered approach in pregnancy management for affected women.

Biography :

Email: lennart.neumann@googlemail.com