Survival and prognostic factors of ovarian cancers in a tertiary hospital in Malaysia

8^th Euro Global Summit on Cancer Therapy

November 03-05, 2015 Valencia, Spain

Bachok Norsa�adah, Lokman Najihah and Abd Hamid Siti-Azrin

Universiti Sains Malaysia, Malaysia

Posters-Accepted Abstracts: J Cancer Sci Ther

Abstract :

Ovarian cancer is one of the most common cancers, leading to death among women in Malaysia. Globally, ovarian cancer has poor mortality rate and short survival rate. The objectives of this study were to determine the survival and prognostic factors of ovarian cancer patients in a tertiary hospital in Malaysia. A retrospective cohort study was conducted on 127 ovarian cancer patients registered from 1st January 2002 until 31st December 2011. Malignant ovarian cancer patients confirmed with histological were selected with inclusion and exclusion criteria. Patients were then followed up until December 2012. Data were analyzed using Kaplan Meier and multiple Cox proportional hazard regression analysis. The overall five-year survival probability of ovarian cancer was 35.2%. (95% confidence interval (CI): 25.7, 50.1) with median survival time was 38 months (95% CI: 25.7, 50.1). The significant prognostic factors were FIGO stage (adjusted hazard ratio (AHR): 2.53; 95% CI: 1.44, 4.45), loss of appetite (AHR: 1.95; 1.23, 3.11) and presence of pleural effusion (AHR: 1.98; 1.19, 3.30). The overall survival probabilities of ovarian cancer were low and an intervention is needed to reduce the mortality and improve quality of life among survivors.

Biography :

Email: norsaadah@usm.my