Synthesis and bioassay of natural macrocyclic peptide

International Conference on Pharmacognosy

March 03-04, 2022 | Webinar

Mohamed Elagawany and Mohame A. Ibrahim

Damanhour University, Egypt

Scientific Tracks Abstracts: J Pharm Nat Prod

Abstract :

Cyclic peptides now draw considerable attention as potential therapeutics due to their roles as mediators of key biological functions together with low toxicity and high specificity. Well-known examples of cyclic peptide drugs include the natural antibiotic vancomycin, hormone oxytocine, neuropeptide vasopressin and antibiotics cyclosporine and tyrocidine.A facile and economic strategy was developed to synthesize naturally occurring macrocyclic peptides Rollo amide A and B in a good yield.

Biography :

Mohamed Elagawany has completed his PhD at the age of 28 years from Zagazig University in collaboration with University of Florida. He is associate professor at Department of Pharmaceutical chemistry, Damanhour University, Egypt. He has published more than 30 papers in reputed journals.