Synthesis and characterization of fluorescence MoS2 dots for biomedical applications

8^th International Conference and Exhibition on Lasers, Optics & Photonics

November 15-17, 2017 | Las Vegas, USA

IK-Jun Yeon, Md Nafiujjaman and Yong-Kyu Lee

Korea National University of Transportation, South Korea

Posters & Accepted Abstracts: J Laser Opt Photonics

Abstract :

Recently, two-dimensional (2D) layered nanomaterials have triggered intensive interest due to the intriguing physicochemical properties that stem from a quantum size effect connected with their ultra-thin structure. In particular, 2D molybdenum disulfide (MoS2), as an emerging class of stable inorganic graphene analogs with an intrinsic finite band gap, would possibly complement or even surpass graphene in different fields. In this study, we have used a facile and simple approach for preparing fluorescence molybdenum disulfide surface passivized by polyethylene glycol (PEG-MoS2) using a one-step reaction, pristine molybdenum disulfide and polyethylene glycol as starting materials. Synthesized PEG-MoS2 showed excellent fluorescence properties with blue color emission under the 365 nm UV lamp compared to fluorescence MoS2. The PL quantum yield of the PEG- MoS2 was about 10% which is higher than fluorescence MoS2. According to morphology, the size of PEG-MoS2 is around 50 nm in diameter where MoS2 is less than 10 nm. We also investigated cell uptake study on cells and found our synthesized PEG-MoS2 was successfully taken up in cells. According to in vitro cellular cytotoxicity studies, there is no cytotoxicity in cells at 200 �¼g/mL concentration of PEG-MoS2. Finally, we can summarize that PEG-MoS2 would be promising material for biomedical applications apart from graphene materials.

Biography :

Yong-Kyu Lee has completed his PhD from Gwangju Institute of Science and Technology and Post-doctoral studies from Georgia Institute of Technology Department of Biomedical Engineering (USA). He is the Professor/Director of Chemical & Biological Engineering and 4D Biomaterial Research Center. He has published more than 100 papers in reputed journals and 30 registered patents (corresponding author).