The efficacy of platelet gel derived from umbilical cord blood on diabetic foot ulcers: A double blind randomized clinical trial

International Conference on Metabolic Syndromes

October 17-18, 2016 Rome, Italy

Seyedeh Esmat

Royan Institute, Iran

Posters & Accepted Abstracts: J Metabolic Synd

Abstract :

Introduction: Type 2 diabetes is one of the most prevalent disease thorough the world. The foot ulcers are severe complications of this disease. Foot ulcers induce high rate of morbidity, impair quality of life and brings about extreme costs to health service providers and give rise to waste of time. Recently, platelet-rich plasma (PRP) and platelet gel (PG) have been used for the treatment of chronic wounds. In the present randomized, double blind, placebo-controlled study, platelet gel derived from umbilical cord blood (UCB) was used to heal the diabetic foot. Method: The patients were randomly divided into three groups, under the categories of platelet gel (PG), poor platelet plasma (PPP) and lubricant gel (placebo) (ratio 1:1:1). The processes of gels application were launched for the subject of each group twice per week with three to four day interval. This mechanism protracted for eight weeks. After completion of eight weeks, the patients were followed up after two weeks and then continued for nine months with one month interval. Result: 30 patients underwent statistical analysis. Except for diastolic blood pressure which was significant between groups, there were no statistically significant differences in patients� baseline demographics. No significant differences were detected between groups at baseline of wounds (P=0.09). The results revealed that there is no statistically significant interaction among three groups within the scope of follow up time. Conclusion: The presented study provides evidence that there are no significant differences in the size of wound among placebo, PPP, and PG group.

Biography :

Email: esmat.hosseini_110@yahoo.com