V N Obolenskiy, P S Leval, A Yu Molotschnikov, L G Zaika, V A Kislyakov, K O Braginskiy and S N Golev
SBHI City hospital No 13 of Moscow Healthcare Department, Russian Federation, 115280, Moscow
Posters-Accepted Abstracts: J Nurs Care
Some infections are difficult to treat with systemic antibiotics because of low tissue perfusion (e.g., bone tissue) or due to the formation of biofilms on metallic or polymeric implant, which provokes the occurrence of complications. In addition, systemic injection of a large dose of antibiotics might lead to toxic concentrations. In such cases, topical antibiotics are required as concomitant therapy. Optimal in our opinion is the use of sterile biodegradable material based on collagen sponge containing an antibiotic (gentamicin), having hemostatic properties and prolonged antimicrobial action. We have used this material in combination with the previous vacuum therapy and without it in the treatment of 42 patients with chronic osteomyelitis of long tubular bones, 9 patients with osteomyelitis of the sternum after sternotomy, 13 patients with septic instability of endoprosthetics of big joints, 40 patients with purulent-necrotic processes syndrome diabetic foot, as well as in some patients with complications of abdominal surgeries and chronic wounds. The recurrent purulent processes have been observed only in 2 patients with chronic osteomyelitis, both in the presence of metal implants. All other patients� relapses were not identified in time from several months to 3 years.
Email: gkb13@mail.ru
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