M S Kamenskikh,A. V. Zagatina, N. T. Zhuravskaya,Y.N. Fedotov, D. V. Shmatov
Clinic of Advanced Medical Technologies n.a. Nikolay I. Pirogov, Russia
Saint - Petersburg State University, Russia
Scientific Tracks Abstracts: J Cardiovasc Dis Diagn
Myxofibrosarcoma is one of the most common soft-tissue sarcomas arising
in the limbs of elderly patients. Description of this tumor in the literature
reported that the commonest sites for metastases are lymph nodes and lungs, but
no case reports to date describe solitary metastasis to the heart from peripheral
myxofibrosarcoma lesions.
Herein, we present the first case report of metastasis of peripheral myxofibrosarcoma
to the heart of a 53-year-old female with equivocal non-invasive and -invasive
diagnostic tests, in whom the final diagnosis was made through exploratory surgery.
The positron emission tomographyâ??computed tomography scans and cardiac
magnetic resonance imaging revealed the mass in the right atrium as well as allowing
an in-depth insight in tumour growth, size, site and extent. Echocardiographic
evaluation was beneficial in confirming the tumour and predicting clinical outcome.
Unfortunately transvenous endomyocardial biopsies of the tumour were nondiagnostic.
Thus a more invasive but diagnostic approach to the right atrial mass was
required via an open surgery, to obtain a definitive histological diagnosis.
This case demonstrates the complexity of pairing multi-modality imaging and
invasive techniques to achieve tissue characterization and diagnosis. Despite
advances in multimodality investigations and increasing treatment options, the case
presented a number of diagnostic and management challenges. Further translational
studies are warranted to improve the diagnostic yield and choice of therapy.
Maxim Kamenskikh complited the Medical Academy in 2006, currently he is a leading cardiac surgeon at St. Petersburg state University. Clinic of advanced medical technologies n.a. Pirogov Nikolai Ivanovich. St. Petersburg, Russian Federation.
E-mail: kamen-maksim@yandex.ru
Cardiovascular Diseases & Diagnosis received 427 citations as per Google Scholar report