The value of prostate HistoScanningâ„¢ in men at risk of prostate cancer

International Conference on Prostate Cancer

June 22-24, 2015 Florida, USA

Vincent De Coninck and Johan Braeckman

Posters-Accepted Abstracts: J Cancer Sci Ther

Abstract :

HistoScanningâ?¢ is an ultrasound-based technology that has been developed to distinguish cancerous and noncancerous tissues in solid organs. By extracting and quantifying statistical features from back-scattered ultrasonographic data, it detects specific changes in tissue morphology. This imaging technique was shown to be efficient in a proof of concept study where the images were compared with whole mount pathology. Small tumors above 0.20 mL can be detected, localized and characterized with high accuracy as compared with histology. HistoScanningâ?¢ is applied to detect or to exclude prostate cancer to assist in carrying out geographical targeted biopsies and to support the strategy of active surveillance. Since its inception date, its negative predictive value has been very good allowing to obviate biopsies in most cases. The positive predictive value of a suspicious lesion within the prostate is higher than todayâ??s standard tests (DRE, PSA, TRUS) and is increasing over the years thanks to increasing experience, improvements of the technology and the possibility of performing real time biopsies. HistoScanningâ?¢ has the potential to become a first line diagnostic test of triage test before biopsy as it is a rather simple, fully available, minimal invasive test that can be done and repeated in the urologists practice.