Thermographic evaluation of the efficacy of immunomodulatory formulae for external use to promote tissue regeneration and wound healing

7^th Euro Biosensors and Bioelectronics Conference

July 10-11, 2017 Berlin, Germany

Karwowski W, Skalski A and Sroka R

AGH University of Science and Technology, Poland

Posters & Accepted Abstracts: J Biosens Bioelectron

Abstract :

One of the features of the signaling proteins (SP) is their immuno-modulating pro and anti-inflammatory properties â�� it has been shown in many clinical trials and publications in the world of medical and biochemical literature. Numerous studies have demonstrated the effect of SP and on IL-1, IL-6, IL-8, IL-6 Interleukins, IFN-�³ interferon, TNF-�± factor (tumor necrosis factor) and RFT (reactive oxygen species) as well as MIP-1�± (macrophage inflammatory protein), MCP-1 (monocyte chemotactic protein), which can contribute to the course of inflammation in the wound. The inflammatory phase, which starts in the healing process right after the hemostatic phase, is basically an introduction to the proper healing process. However, an excessive inflammatory phase can lead to obstruction of the healing and the formation of wounds that heal. As mentioned above, SP can influence this healing phase by regulating it. However, the most important, from the point of view of the purpose of the work, is that any immune reaction, and in particular inflammation, is manifested by a change in the tissue temperature at which it occurs and this change in the parameter can be measured. The research worldwide aimed at creating a universal drug/dressing based on SP, the use of which would enable the application in every phase of the healing process. Pharmacokinetic and pharmacodynamics properties, as well as transport capacity, time of release of active substances, biochemical properties, etc., are investigated and adopted various methods of testing efficiency. Polish medical experiment, as part of these studies, is part of these efforts by proposing a solution based on the presented results and to measure the effectiveness of the use of medical imaging, specifically thermography. We planned and prepared for the implementation of a broad clinical trial of 120 people with double blind trials, which aims to demonstrate thermography methods in confirmation of efficiency of specific biochemical solutions. Presenting the legitimacy and recognition of the planned experiment is to show the practical side of the last stage of clinical trials aimed at standardizing the use of SP in the treatment and prevention of difficult to heal wounds.

Biography :

Email: wojciech.karwowski@saintlazarus.pl